Intranasal Angiotensin II in Humans Reduces Blood Pressure When Angiotensin II Type 1 Receptors Are Blocked
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چکیده
منابع مشابه
Intranasal angiotensin II in humans reduces blood pressure when angiotensin II type 1 receptors are blocked.
Intranasal administration of angiotensin II (ANGII) affects blood pressure in a mode different from intravenously administered ANGII via a direct access to the brain bypassing the blood-brain barrier. This clinical study investigated blood pressure regulation after intranasal ANGII administration in healthy humans, whereas systemic, blood-mediated effects of ANGII were specifically blocked. In ...
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متن کاملthe effects of mas receptor antagonist (a779) and renal perfusion pressure on serum nitrite concentration in male and female rats when angiotensin ii receptors 1 & 2 were blocked
introduction: renin angiotensin system has an important role in blood pressure and renal functions. active angiotensin-converting enzyme 2 converts angiotensin i into angiotensin-(1-7) which is a vasodilator hormone and interacts with nitric oxide changes as well as other angiotensin ii receptors. in this study we evaluated the role of mas receptor antagonist (a779) and renal perfusion pressure...
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ژورنال
عنوان ژورنال: Hypertension
سال: 2014
ISSN: 0194-911X,1524-4563
DOI: 10.1161/hypertensionaha.113.02860